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The Pharmaceutical Industry: How Much Is Too Much?

Prevailing wisdom suggests that the market mechanism serves to allocate funding for research and development on diseases in proportion to the expected return on investment for the new drug. Where the market mechanism fails to allocate resources equitably, how can governing bodies correct the failure of the market mechanism to encourage investment in previously neglected diseases? Pharmaceutical firms have largely concentrated their efforts on meeting industrialized market demands. Current efforts to increase access to essential medications in developing countries (notably for HIV/AIDS therapies) inevitably confront the issue of lower prices. How do lower prices interact with the market mechanism to decrease incentives for investment, and to what degree is this acceptable (and by whom)? How can the interests of inventors be balanced with those of the public?

Carey J, Barrett A. Drug Prices: What's Fair? Business Week, Dec 10, 2001.

Connolly C. Price Tag for a New Drug: $802 Million. Findings of Tufts University Study Are Disputed by Several Watchdog Groups. Washington Post, December 1, 2001, A10.

Doha WTO Ministerial 2001. Declaration on the TRIPS Agreement and public health, adopted November 14, 2001.

Editorial: Patent protetion versus public health. Lancet 2001(10 Nov);238(9293).

Schieppati A, Remuzzi G, Garattini S. Modulating the profit motive to meet needs of the less-developed world. Lancet 2001(10 Nov);238(9293):1638-41.

Goozner M. The Price Isn't Right. The American Prospect, Sept 11, 2000.

Gerth J, Stolberg SG. Drug Companies Profit From Research Supported by Taxpayers. New York Times, April 23, 2000.

Weissman R. AIDS and Developing Countries: Democratizing Access to Essential Medicines. Foreign Policy in Focus 1999(Aug);4(23).

Trouiller P, Olliaro PL. Drug development output: what proportion for tropical diseases? Lancet 1999(Jul 10);354(9173):156.

Gross CP, Anderson GF, Powe NR. The relation between funding by the National Institutes of Health and the burden of disease. NEJM 1999(Jun 17);340(24):1881-87.

   
   
 
 

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